Starting from the hypothesis that alcoholics have a specific semantic network which causes a perceptual-processing bias, we tested 30 male inpatients and 20 healthy male controls. Our modified card version of the Stroop color-naming task consisted of a neutral and critical word condition. The results revealed that alcoholic patients showed a small information processing bias under the critical experimental condition (alcohol-related words); although this was only a trend in the expected direction and statistically not significant. However, neuropsychological impairment of the patients was demonstrated with the “standard Stroop procedure”. The most significant deficits were found in the interference task, which requires cognitive flexibility.